Proteins can undergo posttranslational methylation (one-carbon transfer) at one or more nucleophilic side chains. Most common are methylations on nitrogen or oxygen atoms. Methylation on carboxylate side chains cover up a negative charge and add hydrophobicity. N-Methylation of lysines does not alter the cationic charge but does increase hydrophobicity. In particular, dimethylation and trimethylation of lysine side chains in proteins increase both hydrophobicity and steric bulk and can affect protein–protein interactions if they are in an interacting surface.
I'm just a man who likes fitness, travel, and cars. The well-being of the human person in the family links closely to health. I want to give you a piece of advice, which if you follow it, will make you happy in life. You can begin, right now, to feel healthy! Start training! Why me? I'm a genuine exercise geek and love to teach individuals about their bodies and how to create a strong body.